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| Registros recuperados: 19 | |
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| Karri,Veera Venkata Satyanarayana Reddy; Dhandapani,Nagasamy Venkatesh; Mannemala,Sai Sandeep; Radhakrishna,Kollipara; Mulukutla,Shashank; Sudunagunta,Dedeepya. |
| Abstract Lenalidomide (LND) is an anti-cancer drug and an effective derivative of thalidomide used for multiple myeloma therapy. Because of its poor solubility in water, LND is known to cause low oral bioavailability (below 33%), and as a direct consequence of this, the dosing frequency is extended thus increasing risk of toxicity. To improve its bioavailability and sustained release, the present study aims to formulate polymeric nanoparticles (NPs) for LND using [Poly (lactic-co-glycolic acid)] (PLGA) as a polymer. The polymeric NPs were evaluated for particle size, SEM, XRD, drug content, entrapment efficiency (EE), in vitro release studies and in vivo bioavailability studies in rats. The formulated NPs possessed a size of 179±0.9 nm and a zeta potential... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Multiple myeloma/treatment; Lenalidomide/uses; PLGA/sustained release; Polymeric nanoparticles/development; Solubility. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200602 |
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| Rodrigues,Antonio Augusto Marques; Santos,Luana Ferreira dos; Costa,Rayssa Ribeiro da; Félix,Débora Tamara; Nascimento,José Henrique Bernardino; Lima,Maria Auxiliadora Coêlho de. |
| ABSTRACT Yam, cassava, jackfruit seed and mango seed kernel have potential for the extraction and use as starch in the food industry of starch or for the formulation of biodegradable coatings. As a biodegradable coating, starch can be applied in fruits characterized by a fast maturation, such as mango, which requires technologies to increase its shelf life. The aim of this study was to characterize starch from four non-traditional sources and to evaluate their potential as coating for ‘Palmer’ mango fruit. Starches used were extracted from cassava, mango seed kernel, jackfruit seed, and yam, and had their physical, optical, and chemical properties characterized for later use as coatings of ‘Palmer’ mango fruit. Fruits were coated with 3% cassava starch,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amylose; Solubility; Weight loss; Postharvest; Respiratory rate; Shelf life. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542020000100404 |
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| Neumann,Mikael; Nörnberg,José Laerte; Leão,Guilherme Fernando Mattos; Horst,Egon Henrique; Figueira,Danúbia Nogueira. |
| ABSTRACT: The use of nitrogen fertilizers in corn crops for silage can improve both production and, theoretically, nutritional quality, especially carbohydrate and protein fractions, thereby optimizing animal production. Thus, the aim of this study was to evaluate the effect of increasing levels of nitrogen fertilization in carbohydrate and protein fractionation on the resulting corn silage (Zea mays L.). Nitrogen fertilization was carried out in the urea form (45-00-00) in V5 stage, at the following doses: T1: 0kg N ha-1; T2: 45kg N ha-1; T3: 90kg N ha-1; and T4: 135kg N ha-1. Crops were harvested at R4 stage and submitted to ensiling in experimental PVC silos. The chemical composition of the resulting silage was evaluated after silo opening. There was no... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Starch; Organic acids; C fraction; PH; Solubility. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500251 |
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| サビニアーノ, ナオミ S.; 石橋, 憲一; 弘中, 和憲; 山本, 和夫; SABINIANO, Naomy S.; Ishibashi, Ken-ichi; Hironaka, Kazunori; Yamamoto, Kazuo. |
| The effect of temperature on the properties of potato starch during storage at 1, 5 and 10 centigrade for 6 months were determined. The Brabender peak viscosity, final viscosity at 92.5 centigrade breakdown, swelling power, solubility and phosphorus content decreased while initial pasting temperature, temperature at peak viscosity and blue value of the starches increased during storage. Phosphorus content was highly correlated with Brabender peak viscosity and breakdown(r =0.92 and 0.82, respectively, p<0.01). Higher rates of decrease in viscosity and phosphorus content occurred at 1 and 10 centigrade during storage.... |
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Palavras-chave: Potato storage; Potato starch; Brabender viscosity; Swelling power; Solubility; Phosphorus; Blue value; 馬鈴薯貯蔵; 馬鈴薯デンプン; ブラベンダー粘度; 膨潤度; 溶解度; リン含量; 青価. |
| Ano: 1994 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/1862 |
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| Ângelo,Marilene Lopes; Ruela,André Luís Morais; Ferreira,Anna Clara Marques; Ramos,Marcus Vinicus de Faria; Montanari,Cristina Martiniano; Silva,Lucélia Magalhães da; Araújo,Magali Benjamim de. |
| We propose to evaluate the dissolution properties of rosuvastatin calcium (ROSC) capsules in different media to characterize the discriminatory power of the assay method. Dissolution assays were performed in media with different pH, and including the surfactant sodium dodecyl sulfate (SDS). Several immediate-release formulations were manufactured using the commercial raw material characterized as amorphous solid. The hydrophobic adjutant magnesium stearate was employed in some formulations due to its negative effect in the wettability and dissolution efficacy of solid dosages. These formulations showed the lower dissolution efficacy values in media without surfactant; however, when SDS was added to the medium, the dissolution efficacy increased, and the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dissolution; Crystal polymorphism; Solid dosage form; X-ray powder diffractometry; Thermal analysis; Solubility. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100527 |
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| Souza,Camila Prado Cenciani de; Abreu,Cleide Aparecida de; Andrade,Cristiano Alberto de; Abreu,Mônica Ferreira de. |
| Efficient analytical methods for the quantification of plant-available Zn contained in mineral fertilizers and industrial by-products are fundamental for the control and marketing of these inputs. In this sense, there are some doubts on the part of the scientific community as well as of the fertilizer production sector, whether the extractor requested by the government (Normative Instruction No. 28, called 2nd extractor), which is citric acid 2 % (2 % CA) (Brasil, 2007b), is effective in predicting the plant availability of Zn via mineral fertilizers and about the agronomic significance of the required minimal solubility of 60 % compared to the total content (HCl) (Brasil, 2007a). The purpose of this study was to evaluate the alternative extractors DTPA,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Maize; Micronutrients; Industrial waste; Solubility; Zea mays. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-06832013000400018 |
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| Batista,Marcelo Augusto; Pintro,José Carlos; Costa,Antonio Carlos Saraiva da; Tormena,Cássio Antonio; Bonato,Carlos Moacir; Batista,Michelli Fernandes. |
| The corn plants were evaluated with different phosphate fertilizer sources and aluminum (Al) concentrations in a sandy substrate. A totally randomized experiment design was set up with two corn plants in the pots containing 2 kg of a sandy substrate, two phosphate sources (Triple Super Phosphate - TSP or Arad Phosphate - AP) and four Al concentrations. When Al concentrations increased, pH (CaCl2) substrate values decreased. There was an increase in the calcium and phosphorus contents in the sandy substrates that received the TSP and AP sources. The calcium, magnesium, phosphorus, and potassium concentrations of the corn plant's shoot were higher in the TSP than without P and AP sources. When the Al concentration increased, the concentration values of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Zea mays; Phosphate fertilizers; Solubility; Toxicity. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000300004 |
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| Lauter, Lukas; Hochenauer, Roman; Buchegger, Christoph; Bohn, Marcel; Lengauer, Walter. |
| The solubilities of the most common grain -growth inhibitors (GGIs) Cr, V, Ta, Mo, Nb, Zr and certain combinations there of in the binder phase of WC-Co hardmetals as well as hardmetals of the type WCTiC-TiN-TaC-NbC-Co containing an fcc MC carbide (or carbonitride) phase "MC"("WC-MC-Co" hardmetals) were analysed by means of WDS-EPMA. The carbon potential of the binder phase was fixed at its highest and lowest maxima by the presence of either graphite or eta (M6C) phases. In case of low-carbon hardmetals the composition of M6C, and in the MC-containing hardmetals the composition of the MC phase, was analysed. Two types of solubilities were determined. The first type was measured after controlled cool-down from liquid-phase sintering temperature and... |
| Tipo: Text |
Palavras-chave: Hardmetal; Cemented carbides; Grain-growth inhibitor; Nitrogen; Binder phase; Solubility; EPMA. |
| Ano: 2016 |
URL: http://archimer.ifremer.fr/doc/00332/44332/44155.pdf |
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| Sousa,Alexandre Santos de; Borges,Soraia Vilela; Magalhães,Natália Ferreira; Ricardo,Hevandro Vaz; Azevedo,Aline Damico. |
| Powdered tomato was produced by spray drying the tomato pulp. A full 2³ factorial design with the central point was used, varying the feed flow rate (127-276 g/min), air inlet temperature (200-220ºC) and the atomisation speed (25,000-35,000 rpm). The responses analysed were: moisture content, solubility, wettability consistency and colour, but the factors only significantly affected the colour parameter. All the samples became significantly darker and less red with an increase of the variables under study. A low atomisation speed (25,000 rpm) and lower inlet air temperature (220ºC) produced the powders with a higher colour index (a/b) and less darkening. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Spray dried tomato (Lycopersicon esculentum); Colour; Solubility; Wettability. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000400019 |
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| Registros recuperados: 19 | |
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